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Headache is a nonspecific symptom providing a variety of differential diagnoses, mostly benign. Current trends of the Coronavirus disease (COVID-19) demonstrated a rise in thromboembolic complications including thrombus formation in the brain. Headache with neurological symptoms in COVID-19 patients should not be taken lightly. We report a case of a young lady with a history of SARS-CoV-2 infection who complained of persistent headache with vomiting for three days. Neuroimaging investigation concluded the diagnosis of cerebral venous sinus thrombosis (CVST). This case highlights the importance of awareness of CVST in a COVID-19 patient. We also recommend that COVID-19 patients who have symptoms of raised intracranial pressure such as headache and vomiting should ideally be investigated for CVST. Radiological imaging is indicated so that early effective treatment could be given.
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